• 10-06 Zuberova M, Fenckova M, Šimek P, Janeckova L, Dolezal T (2010), Increased extracellular adenosine in adenosine deaminase deficient flies activates a release of energy stores leading to wasting and death. Disease Models & Mechanisms 3 (2010), 773-784.
  • 10-05 Bártů I, Tomčala A, Socha R, Šimek P, Kodrík D (2010), Analysis of lipids mobilized by adipokinetic hormones in the firebug Pyrrhocoris apterus (L.). European Journal of Entomology 107 (2010), 509-520.
  • 10-04 Kodrík D, Marco HG, Šimek P, Socha R, Štys P, Gäde G (2010), The adipokinetic hormones of Heteroptera: a comparative study. Physiological Entomology 35 (2010), 117-127.
  • 10-03 Gäde G, Šimek P (2010), A novel member of the adipokinetic peptide family in a ‘‘living fossil’’, the ice crawler Galloisiana yuasai, is the first identified neuropeptide from the order Grylloblattodea. Peptides 31 (2010), 372–376.
  • 10-02 Zralá J, Kodrík D, Zahradníčková H, Zemek R, Socha R (2010), A novel function of red pigment-concentrating hormone in crustaceans: Porcellio scaber (Isopoda) as a model species. General and Comparative Endocrinology 166 (2010), 330-336.
  • 10-01 Tomčala A, Bártů I, Šimek P, Kodrík D (2010), Locust adipokinetic hormones mobilize diacylglycerols selectively. Comparative Biochemistry and Physiology Part B 156 (2010), 26-37.


  • 09-02 Zahradníčková H, Hušek P, Šimek P (2009), GC separation of amino acid enantiomers via derivatization with heptafluorobutyl chloroformate and Chirasil-L-Val column. Journal of Separation Science 32 (2009), 3919-3924. IF= 2.655.
  • 09-01 Gäde G, Šimek P, Marco HG (2009),The first identified neuropeptide in the insect order Megaloptera: A novel member of the adipokinetic hormone family in the alderfly Sialis lutaria. Peptides 30 (2009), 477– 482. IF = 2.565.


  • 08-10 Hulak M, Paroulek M, Šimek P, Kocour M, Gela D, Rodina M, Linhart O (2008),Water polluted by 17α-methyltestosterone provides successful male sex inversion of common carp (Cyprinus carpio) from gynogenetic offspring. Journal of Applied Ichtyology 24 (2008), 707-710. IF = 0.638.
  • 08-09 Hušek P, Švagera Z, Všianský F, Franeková J, Šimek P (2008), Prolyl-hydroxyproline dipeptide in non-hydrolyzed morning urine and its value in postmenopausal osteoporosis.  Clinical Chemistry and Laboratory. Medicine 46 (2008), 1391-1397. IF = 2.654.
  • 08-08 Zahradníčková H, Hartvich P, Šimek P, Hušek P (2008), Gas chromatographic analysis of amino acid enantiomers in Carbetocin peptide hydrolysates after fast derivatization with pentafluoropropyl chloroformate. Amino Acids 35 (2008), 445-450. IF = 4.132.
  • 08-07 Šimek P, Hušek P, Zahradníčková H (2008), Gas chromatographic-mass spectrometric analysis of biomarkers related to folate and cobalamin status in human serum after dimercaptopropanesulfonate reduction and heptafluorobutyl chloroformate derivatization. Analytical Chemistry 80 (2008), 5776-5782. IF = 5.712.
  • 08-06 Gäde G, Marco HG, Šimek P, Audsley N, Clark KD, Weaver RJ (2008), Predicted versus expressed adipokinetic hormones, and other small peptides from the corpus cardiacum–corpus allatum: A case study with beetles and moths. Peptides 29 (2008), 1124-1139. IF = 2.565.
  • 08-05 Overgaard J, Tomčala A, Soronsen JG, Holmstrup M, Krogha PH, Šimek P, Košťál V (2008), Effects of acclimation temperature on thermal tolerance and membrane phospholipid composition in the fruit fly Drosophila melanogaster. Journal of Insect Physiology 54 (2008), 619-629. IF = 2.155.
  • 08-04 Hušek P, Šimek P, Hartvich P, Zahradníčková H (2008), Fluoroalkyl chloroformates in treating amino acids for gas chromatographic analysis. Journal of Chromatography A 1186 (2008), 391-400. IF = 3.758.
  • 08-03 Zahradníčková H, Jegorov A, Trnka T, Zelenka K (2007), Thiosugars – Derivatization agents for chiral resolution of homoleucines. Journal of Separation Science 31 (2008), 133-136. IF = 2.655.
    08-02 Mráz J, Dušková S, Šimek P, Marečková J, Nohová H, Stránský V (2008), Biological monitoring of exposure to ethylene oxide in the sterilization units. Chemické listy 101 (2008), 234-236. IF = 0.593.
  • 08-01 Streinz L, Hartvich P, Ondráček J, Šimek P, Fejfarová K, Dušek M (2008), (R)-2-{2-[(S)-(20Benzoyloxy-1,10-binaphthyl-2-yl)oxycarbonylamino]-3-phenylpropanamidomethyl} pyridinium picrate acetone solvate. Acta Crystallographica E 64 (2008), 326-327, suppl. 1-13. IF = 0.367.


  • 07-05 Popkov A, Nadvornik M, Kružberska P, Lyčka A, Lehel S, Gillings N (2007), Towards stereoselective radiosynthesis of alpha-[C-11]methylsubstituted aromatic alpha-amino acids a challenge of creation of quaternary asymmetric centre in a very short time. Journal of Labelled Compounds & Radiopharmaceuticals 50 (2007), 370-374.
  • 07-04 Gäde G, Šimek P, Marco HG (2007), Water scorpions (Heteroptera, Nepidae) and giant water bugs (Heteroptera, Belostomatidae): Sources of new members of the adipokinetic hormone/red pigment-concentrating hormone family. Peptides, 28 (2007), 1359-1367.
  • 07-03 Zahradníčková H, Hušek P, Šimek P, Hartvich P, Maršálek B, Holoubek I (2007), Determination of D- and L-amino acids produced by cyanobacteria using gas chromatography on Chirasil-Val after derivatization with pentafluoropropyl chloroformate.  Analytical and Bioanalytical Chemistry 388 (2007), 1815-1822. IF = 3.328.
  • 07-02 Košťál V, Zahradníčková H, Šimek P, Zelený J (2007), Multiple component system of sugars and polyols in the overwintering spruce bark beetle, Ips typographus. Journal of Insect Physiology 53 (2007), 580–586.
  • 07-01 Gäde G, Šimek P, Marco HG (2007), A novel adipokinetic peptide in a water boatman (Heteroptera, Corixidae) and its bioanalogue in a saucer bug (Heteroptera, Naucoridae). Peptides 28 (2007), 594-601.


  • 06-08 Otová B, Václavíková R, Danielová V, Holubová J, Ehrlichová M, Horský S, Souček P, Šimek P, Gut I (2006), Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague-Dawley/Cub rats. European Journal of Pharmaceutical Sciences 29 (2006), 442-450.
  • 06-07 Tomčala A, Tollarová M, Overgaard J, Šimek P, Košťál V (2006), Seasonal acquisition of chill tolerance and restructuring of membrane glycerophospholipids in an overwintering insect: triggering by low temperature, desiccation and diapause progression. Journal of Experimental Biology 209 (2006), 4102-4114.
  • 06-06 Gut I, Ojima I, Vaclavíkova R, Simek P, Horsky S, Linhart I, Soucek P, Kondrova E, Kuznetsova LV, Chen J (2006), Metabolism of new-generation taxanes in human pig, minipig, and rat liver microsomes. Xenobiotica 36 (2006), 772-792.
  • 06-05 Galis I, Šimek P, Narisawa T, Sasaki M, Horiguchi T, Fukuda H, Matsuoka K, A novel R2R3 MYB transcription factor NtMYBJS1 is a methyl jasmonate-dependent regulator of phenylpropanoid-conjugate biosynthesis in tobacco. The Plant Journal 46 (2006), 573-592.
  • 06-04 Gäde G, Šimek P, Clark K, Auerswald L (2006), Unique translational modification of an invertebrate neuropeptide: a phosphorylated member of the adipokinetic hormone peptide family. Biochemical Journal 393 (2006), 705-713.
  • 06-03 Hušek P, Šimek P (2006), Alkyl chloroformates in sample derivatization strategies for GC Analysis. Current Pharmaceutical Analysis 2 (2006), 21-41.
  • 06-02 Zahradníčková H, Bouman E (2006), Optimization of the solid-phase microextraction method in the determination of Ixodes ricinus (L.) volatiles. Journal of Separation Sciences 29 (2006), 236-241.
  • 06-01 Mráz J, Cimlová J, Stránský V, Nohová H, Kičová R, Šimek P, N-Methylcarbamoyl-lysine adduct in globin: a new metabolic product and potential biomarker of N,N-dimethylformamide in humans. Toxicology Letters 162 (2006), 211-218.


  • 05-04Hušek P (2005), Quantitation of amino acids as chloroformates – A return to gas chromatography, in: Quantitation of amino acids and amines by chromatography, ed. I. Molnár-Perl, Elsevier, Amsterdam, p. 2-38, 2005.
  • 05-03 Doleželová E, Žurovec M, Doležal T, Šimek P, Bryant PJ (2005), The emerging role of adenosine deaminases in insects. Insect Biochemistry and Molecular Biology 35 (2005), 381-389.
  • 05-02 Gäde G, Marco HG, Šimek P, Marais E (2005), The newly discovered insect order mantophasmatodea contains a novel member of the adipokinetic hormone family of peptides. Biochemical and Biophysical Research Communnications 330 (2005), 598-603.
  • 05-01 Zahradníčková H, Hartvich P, Holoubek I (2005), Historie a význam chirálních analýz aminokyselin v biologických matricích a životním prostředí. Chemické Listy 99 (2005), 703-710.


  • 04-6 Košťál V, Tamura M, Tollarová M, Chvalová D, Zahradníčková H (2004), Enzymatic capacity for accumulation of polyol cryoprotectants changes during diapause development in the adult red firebug Pyrrhocoris apterus. Physiological Entomology 29 (2004), 344-355.
  • 04-5 Slaninová J, Bennettová B, Nazarov ES, Šimek P, Holík J, Vlasáková V, Hlaváček V, Černý J, Tykva R (2004), Activity and mechanism of action of insect oostatic peptides in flesh fly. Bioorganic Chemistry 32 (2004), 263-273.
    04-4 Socha R, Kodrík D, Šimek P, Patočková M (2004), The kind of AKH-mobilized energy substrates in insects can be predicted without a knowledge of the hormone structure. European Journal of Entomology 101 (2004), 29-35.
  • 04-3 Mráz J, Šimek P, Chvalová D, Nohová H, Šmigolová P (2004), Studies on the methyl isocyanate adducts with globin. Chemico-Biological Interactions 148 (2004), 1-10.
  • 04-2 Václavíková R, Souček P, Svobodová L, Anzenbacher P, Šimek P, Guengerich FP, Gut I (2004), Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs and minipigs. Drug Metabolism and Disposition 32 (2004), 666-674 IF= 3.277.
  • 04-1 Gális I, Kakiuchi Y, Šimek P, Wabiko H (2004), Agrobacterium tumefaciens AK-6b gene modulates phenolic compound metabolism in tobacco. Phytochemistry 65 (2004), 169-179, IF=1.686.


  • 03-7 Košťál V, Berková P, Šimek P (2003), Remodelling of membrane phospholipids during transition to diapause and cold-acclimation in the larvae of Chymomyza costata (Drosophilidae). Comparative Biochemistry and Physiology B–Biochemistry & Molecular Biology 135 (2003), 407-419.
  • 03-6 Hušek P, Matucha P, Vránková A, Šimek P (2003), Simple plasma work-up for a fast chromatographic analysis of homocysteine, cysteine, methionine and aromatic amino acids. Journal of Chromatography B 789 (2003), 311-322. IF=1.913.
  • 03-5 Bouman EAP, Dusbábek F, Šimek P, Zahradníčková H (2003), Methyl 3-chloro-4-methoxybenzoate, a new candidate semiochemical inhibiting copulation behaviour of Ixodes ricinus (L.) males. Physiological Entomology 28 (2003), 276-282. IF=1.280.
  • 03-4 Hronková M, Zahradníčková H, Šimek P (2003), The role of abscisic acid in acclimation of plants cultivated in vitro to ex vitro Biologia Plantarum 46 (2003), 535-541.
  • 03-3 Hušek P, Šimek P, Matucha P (2003), Smoth esterification of di- and tricarboxylic acids with methyl and ethyl chloroformates in gas chromatographic profiling of urinary acidic metabolites. Chromatographia 58 (2003), 623-630. IF=1.230.
  • 03-2 Gäde G, Auerswald L, Šimek P, Marco HG, Kodrík D (2003), Red pigment concentrating hormone is not limited to crustaceans. Biochemical and Biophysical Research Communications 309 (2003), 967-973. IF=2.935.
  • 03-1 Václavíková R, Horský D, Šimek P, Gut I, (2003)), Paclitaxel metabolims in rat and human liver microsomes is inhibited by phenolic antioxicants. Naunyn-Schmiedeberg’s Archives in Pharmacology 368 (2003), 200-209. IF=2.566.


  • 02-7 Šlachta M, Vambera J, Zahradníčková H, Košťál V (2002), Entering diapause is a prerequisite for successful cold-acclimation in adult Graphosoma lineatum (Heteroptera: Pentatomidae). Journal of Insect Physiology 48 (2002), 1031-1039.
  • 02-6 Hodková M, Berková P, Zahradníčková H (2002), Photoperiodic regulation of the phospholipid molecular species composition in thoracic muscles and fat body of Pyrrohocoris apterus (Heteroptera) via an endocrine gland, corpus allatum. Journal of Insect Physiology 48 (2002), 1009-1019. IF=1.49.
  • 02-5 Gális I, Šimek P, Van Onckelen HA, Kakiuchi Y, Wabiko H (2002), Resistance of transgenic seedlings expressing the Agrobacterium tumefaciens C58-6b gene, to growth-inhibitory levels of cytokinin is associated with elevated IAA levels and activation of phenylpropanoid metabolism. Plant and Cell Physiology 43 (2002), 939-950, IF=2.430.
  • 02-4 Hušek P, Šimek P, Tvrzická E (2002), Simple and rapid procedure for determination of individual fatty acids in serum. Analytica Chimica Acta 465 (2002), 433-439, IF=2.073.
  • 02-3 Mráz J, Dušková Š, Gálová E, Nohová H, Šimek P, Linhart I (2002), Improved gas chromatographic–mass spectrometric determination of N-methylcarbamoyl adduct at the N-terminal valine of globin, a metabolic product of the solvent N, N-dimethylformamide. Journal of Chromatography B 778 (2002), 357-365, IF=1.911.
  • 02-2 Šlachta M, Berková P, Vambera J, Košťál V (2002), Physiology of cold acclimation in the non-diapausing adults of Pyrrhocoris apterus (Heteroptera). European Journal of Entomology 99 (2002), 181-187, IF=0.802.
  • 02-1 Kodrík D, Šimek P, Lepša L, Socha R (2002), Identification of the cockroach neuropeptide Pea-CAH-II as a second adipokinetic hormone in the firebug Pyrrhocoris apterus.  Peptides, 23 (2002), 585-587. IF=1.867.


  • 01-3 Hušek P, Šimek P (2001), Advances in amino acid analysis. LC GC North America 19 (2001), 986-999. IF=3.665.
  • 01-2 Košťál V, Šlachta M, Šimek P (2001), Cryoprotective role of polyols independent of the increase in supercooling capacity in diapausing adults of Pyrrhocoris apterus (Heteroptera: Insecta). Comparative Biochemistry and Physiology B 130 (2001), 365-374, IF=0.831.
  • 01-1 Košťál V, Havelka J, Šimek P (2001), Low-temperature storage and cold hardiness in two populations of the predatory midge Aphidoletes aphidimyza, differing in diapause intensity. Physiological Entomology 26 (2001), 320-328, IF=0.931.