Our research is primarily aimed at uncovering biochemical mechanisms underlying organismal responses to environmental and physiological challenges. We are a research group focused on developing and applying advanced bioanalytical methods to study metabolism across a broad range of organisms – from insects and cyanobacteria to plants and humans –  with particular emphasis on polar metabolites, hormones, bioactive peptides, and volatile organic compounds.

We operate a broad range of analytical platforms for targeted and untargeted metabolomics, lipidomics, fluxomics, and related analyses, based on LC-MS and GC-MS technologies. These platforms support both our in-house research and collaborative projects within the interdisciplinary environment of the Biology Centre. LABM contributes to high-impact publications and translates its expertise into applied outputs. These include analytical kits, protocols, and workflows for broader scientific use. A flagship example is the MetAmino® kit for amino acid analysis, developed by LABM and marketed in collaboration with Chromservis (Prague, Czech Republic).

The group is led by Martin Moos and currently consists of 15 researchers and technical staff. We actively collaborate with national and international partners on research projects that benefit from our bioanalytical expertise and methodological innovation.

Latest publications

Hajdušek O., et al. (2026) Disruption of chitin synthases impairs tick feeding and reproduction. Frontiers in Cellular and Infection Microbiology 16 : 1822003.

Javal M., et al. (2026) Integrative -omics approaches reveal mechanisms of combined heat stress and extreme hypoxia tolerance in a Cerambycid beetle larva. Journal of Experimental Biology 229 : jeb251552

Klíma M.,et al. (2026) Structural mechanism and inhibitor discovery for DhhP, a Borrelia burgdorferi cyclic di-AMP phosphodiesterase with an Fe/Mn bimetallic center. Structure 34 : 758–767

Kunzová M., et al. (2026) Reversal of ATP synthase is a key attribute accompanying cellular differentiation of Trypanosoma brucei insect forms. Communications Biology 9 : 680

Willot Q., et al. (2026) Endogenous colony dormancy shapes seasonal cold tolerance in temperate ants. Functional Ecology 00 : 1–12